league impaired movement. A systematic review by Swain et al 113 reported small to large likelihood ratios for the Lachman test (positive likelihood ratio [PLR] = 1. league impaired movement

 
 A systematic review by Swain et al 113 reported small to large likelihood ratios for the Lachman test (positive likelihood ratio [PLR] = 1league impaired movement  Spine impairment data are presented in Table 1

1 / 63. 2015;19(4):722–31. Nocturne plants a nightmare into his target's mind, dealing damage each second for total 80 / 120 / 160 / 200 / 260 (+100% of ability power) over 2 seconds and fearing the target for 1. 2. 5% increased damage against units with impaired movement (airborne, slow, stun, snare, taunt, suppression). Fantasy. If it says immobilized, slows do not count. ago. The following are the current forms of CC in League of Legends: Airborne: A unit that is airborne is unable to control its movement, attack, or cast abilities for the duration. 5% increased damage against units with impaired movement (airborne, slow, stun, snare, taunt, suppression). Nocturne’s Fear duration is 1. Slows stuns roots etc. Ataxia is a loss of coordination, a symptom seen in multiple sclerosis, stroke, alcohol use disorder, and more. The mean MCI test score in the transient LBP developer group was significantly higher than that in the LBP non-developer group (P = . DOI: 10. About The International Parkinson and Movement Disorder Society ® The International Parkinson and Movement Disorder Society (MDS) is a professional society of more than 11,000 clinicians, scientists and other healthcare professionals dedicated to improving the care of patients with movement disorders through education and research. The Paralympic Movement offers sport opportunities for athletes that have an impairment that belongs to one of ten Eligible. Whether it’s the first time in a bowling centre, using portable lanes in school/community setting or representing your state at the National Disability Championships – we aim to support each individual’s opportunity to bowl. 85). 25 / 1. The movement disorders. Press the Attack. It is a service provider issue at that point most likely. b. [Comment to Article : For example, an Athlete 3. Learned nonuse after stroke is a complication that affects many survivors. Attack speed growth increased to 2. ) There is a lot more information available on the Wikia page I. Methods PubMed and Embase were searched before 15 February 2019 for studies comparing people with neck pain with controls using electronic measurements. Automatisms are common during the seizure, and include oral and/or manual automatisms. 6. ago. For children of Primary-school age we. My problems just went away one day. Ataxia. While upper-extremity movement in individuals with neurological disorders such as stroke and spinal cord injury (SCI) has been studied for many years, the effects of spasticity on arm movement have been poorly quantified. One of the ancient darkin, Varus was a deadly killer who loved to torment his foes, driving them almost to insanity before delivering the killing arrow. Disabil Rehabil. Cerebellar type. Impaired upper-limb (UL) function is one of the most common consequences of stroke [1–3], which can severely hamper activities of daily living and reduce quality of life. In this set of movement impairment diagnoses, rather than being sorted by traditional health conditions or diseases, patients are categorized by their type of movement system problem. If learned nonuse persists, it can lead to muscle atrophy and the loss of motor and sensory function. Grants 2. g. Movement system impairment examination and classification. 1. 65 or 29. The reviewed evidence suggests that eye-movements are impaired in mTBI, but future research is required to accurately and robustly establish findings. Compromise of either the static or dynamic stabilizers of the knee will likely result in impaired movement, functional deficits, and potentially both short and long-term disability. 7 incorporated the new Aqua UI, Apache, PHP, MySQL, Tomcat,. Although memory and visuospatial domains are sometimes impaired, executive functions and fluency are most commonly affected in patients with MSA . The disruptions to nearby events like cricket are particularly concerning given the sport’s popularity with Indians and their potential. Purpose Jump-landing assessments provide a means to quantify an individual’s ability to attenuate ground reaction forces, generate lower limb explosive power and maintain joint alignment. Creath,1 Laurence Magder,2 Mark W. Facebook. V6. By comparing impaired voluntary movements between these two groups, we will gain a greater understanding of the effects of the type of spasticity on these movements and,. That's the reason slows are going to. V13. c. A. for your country at an IWBF competition) you must meet BOTH of the following criteria:. Four second cooldown, apploes to damage. Using a change coming to Illaoi in the next. 12 Moved to tier 5 from 3. Ataxia. Short Story: A Talented mage who finds joy at the sight of bending others will, Mobus took it upon himself to master the arts of suppression . Your Account Email Password Remember me Reset Password. 52, P < 0. Orthopedic Impairment: Physical disability caused by a congenital anomaly (e. Q: Pulse - Mobus casts a pulse wave infront of him that lasts . Longmore, and David Goldberger, “The League of the Physically Handicapped and the Great Depression: A. Teamfight TacticsIntroduction. 4. Posted by u/noealz - 1 vote and 2 commentsYea approach velocity and cheap shot, liandry’s torment all have interactions with impaired movement but that doesn’t mean the target needs to be immobilized, it can be easy to mix up because all immobilizing effects will also count as impaired effects. Jungling - LOL - Jungling guide; 2. You. C. It’s a mechanic that is only useful when playing on high MS (80+). Physical damage is dealt by all basic attacks, and is also dealt by some abilities and item effects. For the expanded patch notes, see here. Neurological dysfunction commonly occurs in the upper limb contralateral to the hemisphere of the brain in which stroke occurs; however, the effect on the ipsilesional upper limb (iUL) is poorly understood [1, 2]. This takes place when an individual ignores or avoids their affected limb, often after a stroke has impaired movement on that side. Ataxia may also be caused by an infection or another treatable. The phenomenon of agonist-antagonist muscle coactivation is discussed with respect to its consequences for movement mechanics (such as increasing joint apparent stiffness, facilitating faster movements, and effects on action stability), implication for movement optimization, and involvement of different neurophysiological structures. In humans, between 60 and 80 % of brain neurons are found within the cerebellum [2, 3], highlighting the importance of this brain structure. Paraplegia: The paralysis of the legs and lower part of the body and is. The statistical analyses were conducted using IBM SPSS 27 Statistics for Windows, USA. The number of velocity peaks was used as an indicator for smoothness of movement in this study. Healing: 18-35 (+0. Reduction: The duration is not reduced by crowd control reduction. Pain associated with movement is a sign of spinal injury. neural connections d. Over the last decade, injury incidence (number of new. Orient player on the court and give an area to cover. 1 (5. 03). Basic attacks and damaging abilities deal 10 - 45 (based on level) bonus true damage to slowed or immobilized enemy champions. Zionism is the movement for the self-determination and statehood for the Jewish people in their ancestral homeland, the land of Israel. Teemo's dance references Badgers by Weebl. THC, a psychoactive compound in marijuana, can impair movement and coordination by interacting with brain areas that control movement and by stimulating the release of dopamine. Assessment of bimanual movements, which are frequently impaired in children with cerebral palsy, is highly challenging in clinical practice. This is a focal impaired awareness cognitive seizure with déjà vu. The Canadian disability rights movement arose in the latter half of the 20th century. Different Types of Crowd Control effects. Cast extending above the left elbow: This added 22. Posture and movement planning, preparation, and execution of a goal-directed reaching movement are impaired in individuals with stroke. This study utilized StartReact (SR) responses elicited by loud. H-28Q Apex Turret. WarwickUse Movement Prediction setting in League of Legends is a helpful feature that any player can turn on in the settings menu in the More Options section. Ahri is a champion in League of Legends. This current concept paper proposes that reducing the number of errors committed during motor learning leads to stable performance when attention. 1111/nyas. Cognition Deficits in Parkinson's Disease. Also, here's a shameless twitch plug. Media Program is an online educational resource offering over 6,000 videos for are those that are blind, visually impaired, deaf, hard of hearing, or deaf-blind. Use “people-first language”: refer to “a person with a disability” rather than “the disabled person” or “the disabled”. Taste of Blood. Reduction: The duration is not reduced by crowd control reduction. b. In particular the NLB raised concerns over the conditions in workshops run to provide. Evidence Update. ”. 25 seconds causing them to run away from Nocturne with impaired movement if they do not get out of (465. Owners and managers of property have responded. Description Passive: Damaging basic attacks and ability damage deal 10 − 45 (based on level) bonus true damage to enemy champions affected by certain crowd. Does that mean, for…There’s a loss of control indicator element and it gives you a very big icon of the impairment affecting you. shirley is introduced to her friend's mother. As a fan of EU, I'm glad that G2. This article section only contains champion skins. Standardization and reporting of eye-movement instruments, data collection procedures, processing algorithms and analysis methods are required. moving the victim yourself. Difficulty walking. Cooldown: 4 seconds. , 2014). (2010). Our objective was to describe differences in measures of movement and posture between people with and without neck pain. By Gil Wayne BSN, R. In order to identify risk factors that can be targeted through appropriate training interventions, it is necessary to establish which (scalar) objective. An easy fix for a movement issue that players may experience in League. What are the odds?"- Jorlen. The AFL commenced surveying injuries in 1992, progressing to a comprehensive league-wide injury surveillance system in 1997, in order to methodically and systematically quantify and report injury rates (incidence, prevalence and recurrence) (Orchard & Seward, 2002). This new system will make diagnosis and classification of seizures easier and more accurate. Inspiration. Basic attacks and damaging abilities deal 10 - 45 (based in level) bonus. A unit that is suppressed is unable to control its movement, declare attacks, cast abilities, activate items or use any summoner spell for the duration. After his death at the age of 63, the researchers studied his brain. Second, with the other amount of slow resist from Unflinching you're going to surpass 100% slow resist. For all associated collection items, see Ahri (Collection). I stay a consistent 55 or 56 ping. YesF###. developing a clear sense of appropriate and moral behavior. all cc except silence count towards immobilizes stun, slow, snare/root, suppression, sleep (zoe), polymorph (lulu), fear, and taunt. Timing abnormalities have been reported in many neurological disorders, including Parkinson's disease (PD). 1 AP) health (based on level)Hoy was an accomplished Major League baseball player from 1888 to 1902 and helped to establish signals for "safe" and "out" calls. Abilities refers to a champion's castable spells (by default , , , and ). Certain intervention methods can promote some recovery of UL motor function though their outcome shows high variability and depends on the intensity. Inappropriate timing and scaling deficits also affect the position of one leg relative to the other, causing impaired interlimb coordination. Research has shown that marijuana can affect balance and impair fine motor skills, and higher doses of THC tend to have a greater impact. Philadelphia 76ers Premier League UFC. V5. National Football League players are at risk for orthopaedic injuries because of the high-impact nature of the sport along with the biomechanical movements required; however, injury and health data on retired players are minimal and focus on postconcussion syndrome or diagnoses such as arthritis. Joseph Shapiro, No Pity: People with Disabilities Forging a New Civil Rights Movement (New York: Three Rivers Press, 1994), Kindle edition. g. For the expanded patch notes, see here. . That's the reason slows are going to. The most frequently described neurotoxicities or systemic conditions. Behavior arrest: In this focal, non-motor seizure type, the person freezes and has impaired awareness. Oppression was a tier 5 Defense mastery with 1 rank. If their movement is impaired, they take double damage from this effect. Requires 16 points in Defense. Cerebral palsy, which occurs in two to three out of 1,000 live births, has multiple etiologies resulting in brain injury that affects movement, posture, and balance. Disables are any effects/conditions that can be 'cleansed' by a stunbreak, but there are at least 2 exceptions - Taunt and Fear - they are both soft and hard CCs - can be cleansed with stunbreaks and/or condi cleanse. HealthPassive movement at all joints, and active movement at most joints increased within 2 weeks post-injection (T1), and persisted at 4–6 weeks post-injection. Explain how poor movement patterns and dysfunctional movement strategies can result in injury or reinjury. Disability and. Major sporting leagues in the US, like the NBA basketball league, were also interrupted. Generalized onset seizure. Trouble swallowing. Slow resist, also Slow resistance, is a stat that reduces the strength of multiplicative (= percentage) slows. the brain b. 4. The sport originated in 1946 when Austrian Hanz Lorrenzen and German Sett Reindle developed the game as a way to keep blinded WWII veterans physically active. 2–4 Timing deficits in PD commonly occur in gait and can manifest as slow shuffling strides, an accelerating gait, or highly variable and random stride times. g. There may sensory (auditory), emotional (fear), cognitive (deja vu) or autonomic features (epigastric sensation, tachycardia, colour change) prior to onset of. "Ineffective Movement related to arthritis" is an incorrect entry because the descriptor is incorrect and the diagnostic label is not approved. unable to function normally or safely (as when operating a motor vehicle) because of intoxication by alcohol or drugs. Impaired movement during combat HI there, im making my first oneshot for my friends, and now i am having trouble. Environmental Conditions. You have to do damage after the cc to proc it. Many sports are played by persons with disability outside formal sports movements. Impared movement is any form of movement cc. 3,10,12 Previous research on retired players. Note that attacks or abilities that impair the target will not trigger that bonus damage themselves, unless the target is already impaired. d. Impaired Movement Automaticity and Dual-Tasking: Impairment in the execution of learned movements when performed without directed attention, often occuring during the concurrent performance of cognitive and motor activities or multiple motor activities. Since crowd control effects impact a unit’s ability to engage in combat, these spells are specialized forms of debuffs. Elbow Movement Exercises: 1. Time Warp Tonic - Your potions or biscuits grant 50% of their health and mana immediately and grant you increased movement speed. Approach Velocity improves your chase and follow-up potential. Pelvic shifting. These abilities can be taunts, slows, roots, and even knock-ups. Hextech Micro-Rockets. Damaging champions with impaired movement or actions deals 12 – 30 bonus true damage (based on level). In fact, MI-UE assesses the motor impairment in a patient who has had a stroke evaluating the ability of the patient to hold a cube against gravity, the capacity to flex. Motor control is the "ability to regulate or direct the mechanisms essential. Differentiate between movement, testing, and assessment. Font of Life does not interact with Echoes of Helia's Soul Siphon. Senna. , club foot), impairments caused by disease (e. How you allow a stun to do so much damage is beyond me. There are four types of forced actions (see below). With Cheap Shot, you deal increased damage to any enemy champion with impaired movements. Vision impairment - This category is the level of impairment of the athlete's vision due to trauma or congenital limitations to the eye, visual cortex, or optic pathways. Omega Squad Teemo and Teemo in Legends of Runeterra are voiced by Melissa Hutchison, who also voices Ashe. Special Olympics Unified Sports® teams do that, too and much more. Droopy eyelids. Nasus ages a champion, slowing them by 35%, increasing to 47 / 59 / 71 / 83 / 95% over 5 seconds. This review shows that aging and chronic conditions result in wide-ranging losses in physical. Note that attacks or abilities that. An implicit approach to motor learning suggests that relatively complex movement skills may be better acquired in environments that constrain errors during the initial stages of practice. PD and basal ganglia dysfunction are associated with impaired motor timing. While inside the shroud, Akali becomes invisible and unable to be selected by. For example, a champion with 300 movement speed will be able to walk the distance of three Teemos standing. This is not to be confused with tenacity, which. Children born prematurely are more likely than full-term children to develop motor problems during infancy. National Football League players are at risk for orthopaedic injuries because of the high-impact nature of the sport along with the biomechanical movements required; however, injury and health data on retired players are minimal and focus on postconcussion syndrome or diagnoses such as arthritis. b. Some individual game servers have. Damage to one nerve group, such as the ulnar nerve, is called mononeuropathy. Rails are either 12 or 15 feet long, depending on the league’s preference. C. Cardiac Conditions. Also, this true damage proc is always active against a Gragas. J Bodyw Mov Ther. Highlights. The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Married at First Sight The Real Housewives of Dallas My 600-lb Life Last Week Tonight with John. This is not the fastest way to level up an. 1 Castable during Crowd Control 2 Types of Crowd Control 3 Categories of Crowd Control 3. Prior dislocation, with or without subsequent shoulder stabilization surgery, complicates the clinical presentation and increases the risk of OA progression. Complex partial seizures are now preferably called "focal impaired awareness seizure" or "focal onset impaired awareness seizure. Factors necessary for a diagnosis of cerebral palsy, and. . . Ataxia may cause uncoordinated or clumsy balance, speech or limb movements, and other symptoms. 3,10,12 Previous research on retired players. Cheap Shot's bonus true damage easily procs on impaired enemies. It is liquidly chaotic in aspect, a faceless shadow with cold eyes and armed with wicked-looking. If their movement is impaired, they take double damage from this effect. What Is Cognition? Embodied cognition is the theory that our behaviour comes from more than just the brain. PASSIVE Gain 15% bonus movement speed toward movement-impaired allies or enemies you've impaired ⇒ Gain 7. Will the damage of volibears majestic roar be increased or just the attack that follows after the enemy is already slowed? league-of. This is a decent Rune to take on Annie since her entire kit revolves around stunning (impairing) an enemy or multiple enemies movement. 13. Does slows counts as an inmobilizing effect like Nasus' Wither? Reviewing the upcoming changes for season 11, two have caught my attention, Thornmail and Abyssal Mask, the changes are the folllowing ones: Thornmail's Grievous Wounds will increase by 60% on immobilized enemy champions, and Abyssal Mask will reduce 25% armor and magic. Television. Neural phenomena such as exaggerated tendon tap reflexes explain spastic movement disorder only to a limited. Whether to alter the pedal settings and whether to use the prosthetic foot to drive are important decisions that should be made with professional. !1"! Abstract! Background:"Concussion"is"regarded"as"a"common"injury"in"rugby"league,"however"no"studies" have"explored"the"long;term"neurophysiological"and"cognitive. 75 / 2 / 2. (Base Movement Speed + Flat Movement Bonuses) × (1 + Percentage Movement Bonuses) × Slow Ratio. If you slow a target by 55% then a teammate slows the same target by 35% (Zilean slow with Ashe auto attack), the target will move at 45% movement speed from Zilean. And for the best item that gives movement speed alongside its other buffs it’s none other than the “Duskblade Of Draktharr”. It is also sometimes referred to as psychomotor slowing or psychomotor impairment. 20 bonus AD, +0. Effects. Article PubMed Google Scholar Chiarotto A, Ostelo RW, Boers M, Terwee CB. 5. But unlike Deadman’s Plate, it’s an active slowing item that has 60 seconds cooldown. 1016/S1474-4422. The steps become irregular (excessively variable) in terms of the placement and timing of footfalls on one side relative to the other. Paul K. Flashcards. There are diminishing returns on bonus movement speed between 415 and 490 (penalized at 80%) and an additional diminishing return on movement speed over 490 (penalized at 50%. " International League Against Epilepsy (ILAE) 2017. 625 from 0. 5 seconds. Certain intervention methods can promote some recovery of UL motor function though their outcome shows high variability and depends on the intensity (repetition) of the. d. Brighter colored equipment. [9] Ataxia - This classification deals with the level of decreased coordination between muscle movements typically associated, but not limited to cerebral palsy. Movement Tips for League of Legends - A guide to move faster and dodge more!In this guide I will give you tips to improve your movement in League of Legends. Their attack speed is also reduced by 75% of the slow. This thread is about top lubrication. Abilities refers to a champion's castable spells (by default , , , and ). This bonus is doubled to 15% toward enemy champions whose movement you have impaired. pmid. Ranged champions healing is reduced on minions. Blinded condition doesn’t alter mental state. impaired: [adjective] being in an imperfect or weakened state or condition: such as. League of Legends Runes. If you were in a room and the lights went out you would still have a general idea where things are. Hemiparesis and spasticity are common co-occurring manifestations of hemispheric stroke. 2 million people worldwide take part in Unified Sports, breaking down stereotypes about people with intellectual disabilities in a really fun way. Methods This cross-sectional study was conducted at a hospital in Japan. Judgments about the timing and the magnitude of movement and degree of end-range alignment in specific joints, and the effect on. The disruptions to nearby events like cricket are particularly concerning given the sport’s popularity with Indians and their potential. For the expanded patch notes, see here. National Football League players are at risk for orthopaedic injuries because of the high-impact nature of the sport along with the biomechanical movements required; however, injury and health data on retired players are minimal and focus on postconcussion syndrome or diagnoses such as arthritis. 2 Impaired passive range of movement . . C. This movement disorder affects the part of the brain that controls coordinated movement. 19. • 5 yr. League of Legends Guide. Movement disorders (MDs) are frequently associated with sensory abnormalities. Effects that only cripple attack speed (such as Malphite's Ground Slam, Warden's Mail's Cold Steel, and Frozen Heart's passive) will count as impairing movement. About 10% of the smallest (<1000 grams) preterm infants will develop cerebral palsy. e. So slows will proc Imperial Mandate but not Zekes or Thornmail. It is constituted in the form of an association under the Swiss Civil Code ( articles 60–79 ). For all associated collection items, see Senna (Collection). Causes. ) There is a lot more information available. 1 Crowd Control Effects 1. If you are still struggling get Liandries and shiet tons of CDR. Since that is above 415, the first soft cap applies. Note that attacks and / or abilities that impair the actual target will not trigger that bonus . Text under CC-BY-SA licenseImpared movement is any form of movement cc. The most common joints players reported as symptomatic were lumbar (n = 63; 97%) and cervical spine (n = 58; 89%). Cerebral palsy (CP) is a lifelong congenital condition that causes palsy, or impaired movements, due to brain damage at a very young age. CH-3X Lightning Grenade. Once activated, Randuin’s Omen slows all enemies in a 550 range radius by 99% for 0. Adaptive sports are also known as disability sports, adapted sports, or. Ezreal's Arcane Shift or Shen's Shadow Dash). Cheap Shot has an extremely short cooldown, being 4 seconds. I did the full lube on all the top parts as instructed in the link a few months ago and it's been great. In the early 20th century, at a time when matters surrounding family planning or women’s healthcare were not spoken in public, Margaret Sanger founded the birth control movement and became an outspoken and life-long advocate for women’s reproductive rights. Crowd control effects are essentially specialized forms of debuffs. Strength Cond. ) P. Appending a descriptor, this is a focal impaired awareness cognitive seizure with déjà vu followed by hand automatisms. For League of Legends on the PC, a GameFAQs message board topic titled "for items and runes that require you to immobilize". Thus, the test battery proposed here may also help classifiers. His W E and R do it. Acute neurological side effects in the central nervous system (CNS) are reported in up to 13% of children with acute lymphoblastic leukemia (ALL) [[1], [2], [3], [4]]. This new movement speed will be reduced by 35%. Movement speed (also Move speed), or MS, is a stat that represents the rate at which an entity travels across the map. What happens during focal aware and focal impaired awareness seizures depends on where in the brain the seizure happens and what that part of the brain normally does. 3,10,12 Previous research on retired players. What they mean by "Impaired Movement"? Would Teemo's first ability (Q) benefit from This because it applies Slow?Damaging champions with impaired movement or actions deals 12 – 30 bonus true damage (based on level). At that point, instead of waiting for the champion to start moving after a second or two, the game itself moves the champion. Introduction. 027). Gait impairments in PD have debilitating. reach and grasp movements) prevails. Decreased muscle size and lack of muscle tone. 5. For many of my students with disabilities, completing tasks that require movement, strength, or endurance can be difficult and overwhelming. So if you are standing in a full storm of a level 16 Anivia, you are slowed by 60%. they might be able to implement some sort of “cursor movement softening” software that helps guide the mouse more smoothly towards likely targets, or maybe. Free Download MAC OS X lion 10. No champ should be able to one shot you with a stun. Double vision. Basic research has only just begun to investigate forelimb function after spinal cord injury (Girgis et al. The mean (SD) follow-up time was 8. The term Paralympic sports may also be used interchangeably with parasports, though technically this only refers to sports contested. Background Comprehensive treatment strategies are needed for individuals with glenohumeral joint osteoarthritis (OA), especially when they are young and active. 6%) infants received any phototherapy. This article section only contains champion skins. Approach Velocity. Draven doesn't need more power lategame nor does he need more damage or utility at any point of the game right now. 2014 BLUF Physical, technical and tactical performance can affect recovery responses, although English Championship soccer players did not experience impaired physical. Heal when you damage an enemy champion. League of Legends; for items and runes that require you to immobilize; Topic Archived; More Topics from this Board. Literally one stun, 1500 damage. Impaired neuromuscular control has been associated with muscular imbalances , fatigue , foot type , and asymmetry in movement (131,168,169). Impaired ability to grab objects. 5% increased damage against units with impaired movement (slow, stun, root etc). Etymology. This way, players experience more or less the same level of responsiveness while playing the game, regardless of differing latency levels. Psychomotor agitation is a feeling of anxious restlessness that can lead to unintended movements. Basically title. 2 Other 3 Increasing flat movement speed. Start tracking progress. Note : The following question is for visually Impaired Students only, in Lieu of Q. Teemo's dance. Here are all the movement speed changes coming to the League of Legends PBE in patch 11. Grants 2. Respiratory Conditions. becoming independent in age-appropriate ways. This article section only contains champion skins. Key clinical features signaling the onset of Glut1DS are eye-head movement abnormalities, seizures, neurodevelopmental impairment, deceleration of head growth, and movement disorders.